Highly scalable and more sensitive CRISPR screens using the BD Rhapsody™ Single-Cell Analysis System
CRISPR screens have become the prime discovery tool in modern cell biology. Transcriptomics represents a generic phenotype that is informative across a range of biological questions and disease conditions. Single-cell RNA sequencing (scRNA-seq) can be used to link genetic perturbations elicited by CRISPR/Cas9 to their transcriptomic phenotypes. The BD Rhapsody™ Single-Cell Analysis System employs a targeted scRNA-seq approach that lowers experimental cost and at the same time enhances dynamic range and scalability.
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