Feb 26, 2019

AMPA

Budget friendly AMPA Receptor 2 Research Packs include specific antibodies and pharmacological tools for AMPA receptor research!
Choose from 3 Research Packs:
Antibodies:
Agonists:
CX 546 (#C-210)
Antagonists:
PhTx-74 (#P-120)
p-120

PhTx-74

CX 546 (#C-210)                 bioassay

c-210
Purity: >99%
CAS No.: 215923-54-9
Target: Agonist of AMPA receptors

Alomone Labs CX 546 potentiates GluA1 channels expressed in Xenopus oocytes:

c-210

 

 

 

 

 

 

 

Time course of current reversible potentiation by 12.6, 126 and 630 μM CX 546 (#C-210) of glutamate-elicited currents (100 μM, holding potential -80 mV).

 

Expression of AMPA Receptor 2 (GluA2) in rat cerebellum:
aGC-005
Immnunohistochemical staining of rat cerebellum using Anti-GluR2 (GluA2) (extracellular) Antibody(#AGC-005). A. Co-localization of GluA2 (green) and calbindin D28-K (red) in Purkinje cell dendrites (vertical arrow). B. Distribution of calbindin D28-K. C. Distribution of GluA2. Note that some GluA2 positive fibers (horizontal arrow) that are probable Bergmann glial processes do not stain for GluA2. D. The molecular and Purkinje layer (blue).
Premium
Antibodies:
Agonists:
CX 546 (#C-210)
PEPA (#P-200)
Antagonists:
PhTx-74 (#P-120)
a-266

(RS)-AMPA hydrobromide

YM 90K hydrochloride (#Y-105)            bioassay
y-105
Purity: >99%
CAS No.: 154164-30-4
Target: Antagonist of AMPA receptors

Alomone Labs YM 90K hydrochloride inhibits GluA1 channels heterologously expressed in Xenopus oocytes:

y-105

Time course of reversible current inhibition by 10 μM YM 90K hydrochloride (#Y-105) of glutamate-elicited currents (100 μM, holding potential -80 mV).

 

Guinea pig Anti-GluR2 (GluA2) (extracellular) Antibody (#AGP-073)

Western blot analysis:
AGP-073
Western blot analysis of rat brain membranes:
1. Guinea pig Anti-GluR2 (GluA2) (extracellular) Antibody (#AGP-073), (1:500).
2. Guinea pig Anti-GluR2 (GluA2) (extracellular) Antibody, preincubated with the control peptide antigen.
Western blot analysis:
AGP-073
Western blot analysis of mouse brain lysate:
1. Guinea pig Anti-GluR2 (GluA2) (extracellular) Antibody (#AGP-073), (1:600).
2. Guinea pig Anti-GluR2 (GluA2) (extracellular) Antibody, preincubated with the control peptide antigen.
Deluxe
DNQX disodium salt (#D-130)    bioassay
d-130
Purity: >99%
CAS No.: 1312992-24-7
Target: Antagonist of AMPA/Kainate receptors

Alomone Labs DNQX disodium salt inhibits GluA1 channels expressed in Xenopus oocytes:

d-130

Time course of current reversible inhibition by 50 and 500 µM DNQX disodium salt (#D-130) (at 0 mV) in the presence of 10 μM glutamate. Amplitude change as a result of the application of raising concentrations of DNQX (perfusion duration indicated by the horizontal bar, concentration as indicated).

 

Expression of AMPA Receptor 2 (GluR2) in mouse brain:
AGC-005-AG

 Immunohistochemical staining of frozen free-floating of the molecular layer of the mouse cerebellum using Anti-GluR2 (GluA2) (extracellular)-ATTO-488 Antibody (#AGC-005-AG), (1:20). Both dendrites of Purkinje cells (arrows) were stained (green). DAPI counterstain (blue) helps define the layers: granule (G), Purkinje (P), and molecular (M).

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All you need for AMPA Receptors Research!

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